Title : Pharmacokinetics of bambuterol in subjects homozygous for the atypical gene for plasma cholinesterase.

Pub. Date : 1998 May

PMID : 9643621






2 Functional Relationships(s)
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1 AIMS: It has been assumed that both plasma cholinesterase (EC 3.1.1.8) and oxidative enzymes are needed for optimum formation of the bronchodilator terbutaline from its biscarbamate prodrug bambuterol. Terbutaline butyrylcholinesterase Homo sapiens
2 Nevertheless, the subjects with atypical cholinesterase were able to produce terbutaline as efficiently as normal subjects. Terbutaline butyrylcholinesterase Homo sapiens