Title : Mite antigen-induced IL-4 and IL-13 production by basophils derived from atopic asthma patients.

Pub. Date : 1998 Apr

PMID : 9641578






3 Functional Relationships(s)
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1 The production of these cytokines was significantly suppressed by the anti-asthma drugs theophylline (IL-4, p<0.001, n=6; IL-13, p<0.001, n=10) and dexamethasone (IL-4, p<0.001, n=15; IL-13, p<0.001, n=10). Theophylline interleukin 4 Homo sapiens
2 The production of these cytokines was significantly suppressed by the anti-asthma drugs theophylline (IL-4, p<0.001, n=6; IL-13, p<0.001, n=10) and dexamethasone (IL-4, p<0.001, n=15; IL-13, p<0.001, n=10). Theophylline interleukin 4 Homo sapiens
3 The inhibitory effect of dexamethasone and theophylline on allergic inflammation may be due to the inhibition of IL-4 and IL-13 production not only by T cells but also by basophils. Theophylline interleukin 4 Homo sapiens