Pub. Date : 1998 May
PMID : 9630454
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Phenobarbital (PB)-mediated induction of five forms of cytochrome P450 (CYP2B1, CYP2B2, CYP3A1, CYP2A1, and CYP2C6) and epoxide hydrolase is highly suppressed, at the transcriptional level, in Wistar Furth (WF) relative to Fischer 344 (F344) female rats. | Phenobarbital | cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 | Rattus norvegicus |
2 | Phenobarbital (PB)-mediated induction of five forms of cytochrome P450 (CYP2B1, CYP2B2, CYP3A1, CYP2A1, and CYP2C6) and epoxide hydrolase is highly suppressed, at the transcriptional level, in Wistar Furth (WF) relative to Fischer 344 (F344) female rats. | Phenobarbital | cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 | Rattus norvegicus |
3 | The LFD suppressed PB-induction of CYP mRNA and protein in WF but not F344 rats. | Phenobarbital | cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 | Rattus norvegicus |