Title : Roles of cytochromes P450 1A2 and 3A4 in the oxidation of estradiol and estrone in human liver microsomes.

Pub. Date : 1998 Jun

PMID : 9625734






1 Functional Relationships(s)
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1 Of seven cDNA-expressed human cytochrome P450 (P450) enzymes (P450s 1A2, 2B6, 2C9, 2C19, 2D6, 2E1, and 3A4) examined, P450 1A2 was the most active in catalyzing 2- and 4-hydroxylations of estradiol and estrone. Estrone cytochrome P450 family 2 subfamily B member 6 Homo sapiens