Title : Metastasis suppression by the standard CD44 isoform does not require the binding of prostate cancer cells to hyaluronate.

Pub. Date : 1998 Jun 1

PMID : 9622073






2 Functional Relationships(s)
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1 In this study, an investigation was made to resolve whether the ability of the standard CD44 isoform to suppress metastasis of the AT3.1 prostate cancer cells critically requires enhanced hyaluronate binding. hyaluronate CD44 molecule (Indian blood group) Rattus norvegicus
2 Expression of the wild-type standard CD44 isoform increased the hyaluronate binding of prostate cancer cells and suppressed their metastatic ability without suppressing their tumorigenicity. hyaluronate CD44 molecule (Indian blood group) Rattus norvegicus