Pub. Date : 1998 May 7
PMID : 9620551
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Human male germ cell tumor resistance to cisplatin is linked to TP53 gene mutation. | Cisplatin | tumor protein p53 | Homo sapiens |
| 2 | The simplest explanation for the resistance of this subset of GCTs that are resistant to cisplatin-based chemotherapy, is the inability of the cells to mount an apoptotic response following exposure due to a functionally inactivating mutation in the TP53 gene. | Cisplatin | tumor protein p53 | Homo sapiens |