Title : Pirarubicin might partly circumvent the P-glycoprotein-mediated drug resistance of human breast cancer tissues.

Pub. Date : 1998 Mar-Apr

PMID : 9615748






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Pirarubicin might partly circumvent the P-glycoprotein-mediated drug resistance of human breast cancer tissues. pirarubicin ATP binding cassette subfamily B member 1 Homo sapiens
2 Pgp was expressed in 23.5% (12/51) specimens and the efficacy of anthracyclines was reduced in Pgp-positive breast cancer tissues, although this reduction was low in THP with a statistically significant difference when comparing with DXR and EPIR. pirarubicin ATP binding cassette subfamily B member 1 Homo sapiens