Title : Five-lipoxygenase inhibitors reduce Panc-1 survival: the mode of cell death and synergism of MK886 with gamma linolenic acid.

Pub. Date : 1998 Mar-Apr

PMID : 9615721






2 Functional Relationships(s)
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1 The 5-lipoxygenase inhibitors ETYA, SC41661A and MK886 reduced the proliferation and viability of Panc-1 human pancreatic cancer cells. MK-886 arachidonate 5-lipoxygenase Homo sapiens
2 When gamma linolenic acid was combined with MK886, the more effective of the two 5-lipoxygenase inhibitors, a synergistic reduction in Panc-1 cell number and viability occurred. MK-886 arachidonate 5-lipoxygenase Homo sapiens