Title : Galanin inhibits glucagon-like peptide-1 secretion through pertussis toxin-sensitive G protein and ATP-dependent potassium channels in rat ileal L-cells.

Pub. Date : 1998 Apr

PMID : 9614355






1 Functional Relationships(s)
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1 Pretreatment of cells with 200 ng/ml pertussis toxin for 3 h, or incubation with the ATP-sensitive K+ channel blocker disopyramide (200 microM), prevented the inhibition by galanin of bombesin- and GIP-stimulated GLP-1 secretion. Disopyramide gastric inhibitory polypeptide Rattus norvegicus