Title : Cap43, a novel gene specifically induced by Ni2+ compounds.

Pub. Date : 1998 May 15

PMID : 9605764






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Cap43, a novel gene specifically induced by Ni2+ compounds. Nickel(2+) N-myc downstream regulated 1 Homo sapiens
2 We have found that the primary signal for Cap43 induction was an elevation of free intracellular Ca2+ caused by Ni2+ exposure because Cap43 was induced by calcium ionophores and its induction was attenuated by bis-(O-aminophenyl)-ethane-N,N,N",N"-tetraacetic acid tetra(acetoxymethyl)-ester, a chelator of intracellular Ca2+. Nickel(2+) N-myc downstream regulated 1 Homo sapiens
3 We have found that the primary signal for Cap43 induction was an elevation of free intracellular Ca2+ caused by Ni2+ exposure because Cap43 was induced by calcium ionophores and its induction was attenuated by bis-(O-aminophenyl)-ethane-N,N,N",N"-tetraacetic acid tetra(acetoxymethyl)-ester, a chelator of intracellular Ca2+. Nickel(2+) N-myc downstream regulated 1 Homo sapiens