Title : Involvement of the proliferating cell nuclear antigen (PCNA) in DNA repair induced by alkylating agents and oxidative damage in human fibroblasts.

Pub. Date : 1998 Apr

PMID : 9600342






2 Functional Relationships(s)
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Protein Name
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1 Treatment with the alkylating agents methylmethane sulfonate and N-methyl-N"-nitro-N-nitrosoguanidine resulted in the rapid and dose-dependent increase in the nuclear binding of PCNA. Methyl Methanesulfonate proliferating cell nuclear antigen Homo sapiens
2 In these conditions, treatment with hydrogen peroxide or methylmethane sulfonate, resulted in an increase in nuclear-bound PCNA in the G1 and in the G2 + M compartments, but not in S phase. Methyl Methanesulfonate proliferating cell nuclear antigen Homo sapiens