Title : Constitutive and cytokine-inducible expression of prion protein gene in human neural cell lines.

Pub. Date : 1998 Feb

PMID : 9600205






1 Functional Relationships(s)
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1 In SK-N-SH cells, a 48 hour (h) treatment with 100 ng/ml IL-1beta, 100 ng/ml TNF-alpha, or 100 nM phorbol 12-myristate 13-acetate induced a 2.7- to 4.2-fold increase in the level of PrP mRNA, while the exposure to 100 ng/ml IFN-gamma resulted in a 50% decrease. sk-n interleukin 1 beta Homo sapiens