Pub. Date : 1997 Aug
PMID : 9600114
10 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | 12-O-tetradecanoylphorbol-13-acetate (TPA) downregulates expression of CD30 in erythroleukemia cell line K562. | Tetradecanoylphorbol Acetate | TNF receptor superfamily member 8 | Homo sapiens |
| 2 | 12-O-tetradecanoylphorbol-13-acetate (TPA) downregulates expression of CD30 in erythroleukemia cell line K562. | Tetradecanoylphorbol Acetate | TNF receptor superfamily member 8 | Homo sapiens |
| 3 | In this study, modulation of the CD30 molecule was investigated by the treatment with 12-O-tetradecanoyl-phorbol-13-acetate (TPA). | Tetradecanoylphorbol Acetate | TNF receptor superfamily member 8 | Homo sapiens |
| 4 | In this study, modulation of the CD30 molecule was investigated by the treatment with 12-O-tetradecanoyl-phorbol-13-acetate (TPA). | Tetradecanoylphorbol Acetate | TNF receptor superfamily member 8 | Homo sapiens |
| 5 | When cultures were supplemented with TPA, CD30 transcript was downregulated in a dose- and time-dependent manner in the erythroleukemia cell line K562. | Tetradecanoylphorbol Acetate | TNF receptor superfamily member 8 | Homo sapiens |
| 6 | This consecutive reduction of both the transcript and proteins suggests that TPA directly inhibits the transcriptional step of CD30, and subsequently CD30 molecules would decrease on the cell surface. | Tetradecanoylphorbol Acetate | TNF receptor superfamily member 8 | Homo sapiens |
| 7 | This consecutive reduction of both the transcript and proteins suggests that TPA directly inhibits the transcriptional step of CD30, and subsequently CD30 molecules would decrease on the cell surface. | Tetradecanoylphorbol Acetate | TNF receptor superfamily member 8 | Homo sapiens |
| 8 | The addition of H-7 recovered the inhibitory effect of TPA, indicating that PKC is involved in the transcription of CD30. | Tetradecanoylphorbol Acetate | TNF receptor superfamily member 8 | Homo sapiens |
| 9 | When either 2 micrograms/ml actinomycin D or 20 micrograms/ml cycloheximide was added simultaneously with TPA to the culture, the repressive effect of TPA on CD30 was abolished. | Tetradecanoylphorbol Acetate | TNF receptor superfamily member 8 | Homo sapiens |
| 10 | When either 2 micrograms/ml actinomycin D or 20 micrograms/ml cycloheximide was added simultaneously with TPA to the culture, the repressive effect of TPA on CD30 was abolished. | Tetradecanoylphorbol Acetate | TNF receptor superfamily member 8 | Homo sapiens |