Pub. Date : 1998 Apr
PMID : 9594630
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | To quantify the expression of the gene encoding P-gp (multidrug resistance 1; MDR1) and assess P-gp function, we developed competitive reverse transcription-polymerase chain reaction (RT-PCR) assay using heterologous competitor RNA and flow cytometric analysis using rhodamine 123 (Rh123; an artificial substrate for P-gp), respectively. | Rhodamine 123 | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 2 | To quantify the expression of the gene encoding P-gp (multidrug resistance 1; MDR1) and assess P-gp function, we developed competitive reverse transcription-polymerase chain reaction (RT-PCR) assay using heterologous competitor RNA and flow cytometric analysis using rhodamine 123 (Rh123; an artificial substrate for P-gp), respectively. | Rhodamine 123 | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 3 | To quantify the expression of the gene encoding P-gp (multidrug resistance 1; MDR1) and assess P-gp function, we developed competitive reverse transcription-polymerase chain reaction (RT-PCR) assay using heterologous competitor RNA and flow cytometric analysis using rhodamine 123 (Rh123; an artificial substrate for P-gp), respectively. | Rhodamine 123 | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 4 | The MDR1 expression in leukemia sublines quantified by competitive RT-PCR assay showed linearity over a wide range, and the results were parallel with those of MDR1 expression measured by Northern blot analysis, the P-gp antigen expression measured by flow cytometric analysis using MRK16, P-gp function analysis by Rh123 dye-efflux assay, and MDR phenotype. | Rhodamine 123 | ATP binding cassette subfamily B member 1 | Homo sapiens |