Title : Arginine vasopressin enhances sympathetic constriction through the V1 vasopressin receptor in human saphenous vein.

Pub. Date : 1998 Mar 10

PMID : 9580082






2 Functional Relationships(s)
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1 AVP (3x10[-9] mol/L) enhanced the contractions elicited by electrical field stimulation at 1, 2, and 4 Hz (by 80%, 70%, and 60%, respectively) and produced a leftward shift of the concentration-response curve to norepinephrine (half-maximal effective concentration decreased from 6.87x10[-7] to 1.04x10[-7] mol/L; P<.05). Norepinephrine arginine vasopressin Homo sapiens
2 CONCLUSIONS: The results suggest that low concentrations of AVP facilitate sympathetic neurotransmission and potentiate constrictor effects of norepinephrine in human saphenous veins. Norepinephrine arginine vasopressin Homo sapiens