Title : Dose-dependent CSF acetylcholinesterase inhibition by SDZ ENA 713 in Alzheimer's disease.

Pub. Date : 1998 Apr

PMID : 9576639






2 Functional Relationships(s)
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1 INTRODUCTION: This study evaluates the activity of SDZ ENA 713, a centrally-selective acetylcholinesterase (AChE) inhibitor, in the cerebral spinal fluid (CSF) of patients with Alzheimer"s disease (AD), and its relationship to central and peripheral pharmacokinetic parameters. Sulfadiazine acetylcholinesterase (Cartwright blood group) Homo sapiens
2 CONCLUSION: Rapid, sustained, dose-dependent inhibition of CSF AChE suggests that SDZ ENA 713 has therapeutic potential in AD patients. Sulfadiazine acetylcholinesterase (Cartwright blood group) Homo sapiens