Pub. Date : 1998 Mar
PMID : 9576062
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We demonstrated that the formation of prostaglandin E2 (PGE2) is highly dependent on the expression of PGHS-2 enzyme in these cells. | Dinoprostone | prostaglandin-endoperoxide synthase 2 | Mus musculus |
| 2 | We demonstrated that the formation of prostaglandin E2 (PGE2) is highly dependent on the expression of PGHS-2 enzyme in these cells. | Dinoprostone | prostaglandin-endoperoxide synthase 2 | Mus musculus |
| 3 | TNF-alpha-induced PGE2 production was evident after 12 h and was associated with a significant TNF-alpha-mediated increase in PGHS-2 immunoreactive protein. | Dinoprostone | prostaglandin-endoperoxide synthase 2 | Mus musculus |
| 4 | A specific PGHS-2 inhibitor, NS-398, completely abolished the TNF-alpha-mediated increase in PGE2 production, suggesting that the PGE2 formed in response to TNF-alpha was derived from PGHS-2. | Dinoprostone | prostaglandin-endoperoxide synthase 2 | Mus musculus |
| 5 | A specific PGHS-2 inhibitor, NS-398, completely abolished the TNF-alpha-mediated increase in PGE2 production, suggesting that the PGE2 formed in response to TNF-alpha was derived from PGHS-2. | Dinoprostone | prostaglandin-endoperoxide synthase 2 | Mus musculus |
| 6 | A specific PGHS-2 inhibitor, NS-398, completely abolished the TNF-alpha-mediated increase in PGE2 production, suggesting that the PGE2 formed in response to TNF-alpha was derived from PGHS-2. | Dinoprostone | prostaglandin-endoperoxide synthase 2 | Mus musculus |
| 7 | A specific PGHS-2 inhibitor, NS-398, completely abolished the TNF-alpha-mediated increase in PGE2 production, suggesting that the PGE2 formed in response to TNF-alpha was derived from PGHS-2. | Dinoprostone | prostaglandin-endoperoxide synthase 2 | Mus musculus |