Title : Down-regulation of CXCR2 expression on human polymorphonuclear leukocytes by TNF-alpha.

Pub. Date : 1998 May 1

PMID : 9574558






1 Functional Relationships(s)
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1 These findings suggest that TNF-alpha down-regulates CXCR2 expression on PMNs and modulates IL-8-induced biologic responses, leading to the intravascular retention of PMNs with an enhanced production of reactive oxygen metabolites. Oxygen C-X-C motif chemokine ligand 8 Homo sapiens