Title : Induction of Fas ligand in murine bone marrow NK cells by bacterial polysaccharides.

Pub. Date : 1998 May 1

PMID : 9574536






1 Functional Relationships(s)
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1 The LPS- or mannuronan-induced cytotoxicity was due to increased Fas ligand (FasL) expression by BMC, since 1) Fas-transfected L1210-Fas target cells were more susceptible to lysis than the Fas(low)-expressing parent L1210 cells, 2) stimulated BMC from FasL-defective gld/gld mice were not cytolytic and, 3) the cytolytic activity of normal BMC was inhibited by a Fas-Fc fusion protein. ammonium ferrous sulfate Fas ligand (TNF superfamily, member 6) Mus musculus