Title : Synergistic effect of MNU and DMBA in mammary carcinogenesis and H-ras activation in female Sprague-Dawley rats.

Pub. Date : 1997 Nov 25

PMID : 9570390






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Of the mammary carcinomas induced by the combined application of MNU and DMBA (group 6), all 11 tumors from five rats showed the GGA to GAA transitional mutation in H-ras codon 12 (38%) and all 18 tumors from the other 10 rats remained as wild-type. Methylnitrosourea HRas proto-oncogene, GTPase Rattus norvegicus