Title : Physicochemical, molecular-orbital and electronic properties of acephate and methamidophos.

Pub. Date : 1998 Jan

PMID : 9568380






1 Functional Relationships(s)
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1 We propose that, similar to a previous model for cationic inhibitors of AChE (13), the P = O delta- group of Me forms hydrogen bonds within the oxyanion-hole causing the leaving group (-SCH3) to orient towards the "gorge" opening. Hydrogen acetylcholinesterase (Cartwright blood group) Homo sapiens