Pub. Date : 1998 Feb
PMID : 9551703
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | OBJECTIVE: Losartan is metabolised to its active metabolite E-3174 by CYP2C9 and CYP3A4 in vitro. | losartan carboxylic acid | cytochrome P450 family 2 subfamily C member 9 | Homo sapiens |
| 2 | This implicates that, in man, CYP2C9 is a major enzyme for the formation of E-3174 from losartan. | losartan carboxylic acid | cytochrome P450 family 2 subfamily C member 9 | Homo sapiens |