Title : Fluconazole but not itraconazole decreases the metabolism of losartan to E-3174.

Pub. Date : 1998 Feb

PMID : 9551703






1 Functional Relationships(s)
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1 OBJECTIVE: Losartan is metabolised to its active metabolite E-3174 by CYP2C9 and CYP3A4 in vitro. losartan carboxylic acid cytochrome P450 family 3 subfamily A member 4 Homo sapiens