Title : Mutations of the flavin-containing monooxygenase gene (FMO3) cause trimethylaminuria, a defect in detoxication.

Pub. Date : 1998 May

PMID : 9536088






2 Functional Relationships(s)
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1 Mutations of the flavin-containing monooxygenase gene (FMO3) cause trimethylaminuria, a defect in detoxication. 4,6-dinitro-o-cresol flavin containing dimethylaniline monoxygenase 3 Homo sapiens
2 We show here that mutations in the human flavin-containing monooxygenase isoform 3 gene ( FMO3 ) impair N -oxygenation of xenobiotics and are responsible for the trimethylaminuria phenotype. 4,6-dinitro-o-cresol flavin containing dimethylaniline monoxygenase 3 Homo sapiens