Pub. Date : 1998 Apr
PMID : 9536016
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Pretreatment with NS398 (COX-2 inhibitor) significantly decreased ROS generation indicating the involvement of COX-2 in KCN-induced oxidant generation. | Reactive Oxygen Species | mitochondrially encoded cytochrome c oxidase II | Homo sapiens |
| 2 | These findings show that activation of phospholipase A2 and subsequent metabolism of arachidonic acid by the COX-2 and LOX pathways and NOS contribute to cyanide-induced ROS production. | Reactive Oxygen Species | mitochondrially encoded cytochrome c oxidase II | Homo sapiens |