Title : Fluorescent probing with felodipine of the dihydropyridine receptor and its interaction with the ryanodine receptor calcium release channel.

Pub. Date : 1998 Mar 17

PMID : 9514900






2 Functional Relationships(s)
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1 In both cardiac SLM and SR, the felodipine fluorescence was sensitive to conformational changes of the DHPR, as diltiazem that binds to DHPR at a separate site altered the values of both the Kd and the Hill coefficient characteristic for felodipine binding. Diltiazem calcium voltage-gated channel subunit alpha1 S Homo sapiens
2 In both cardiac SLM and SR, the felodipine fluorescence was sensitive to conformational changes of the DHPR, as diltiazem that binds to DHPR at a separate site altered the values of both the Kd and the Hill coefficient characteristic for felodipine binding. Diltiazem calcium voltage-gated channel subunit alpha1 S Homo sapiens