Pub. Date : 1998 Feb
PMID : 9506896
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | However, mag1 and apn1 mutants that are also defective in nucleotide excision repair are extremely sensitive to MMS-induced killing and the effects are synergistic. | Methyl Methanesulfonate | DNA-(apurinic or apyrimidinic site) lyase APN1 | Saccharomyces cerevisiae S288C |
| 2 | It was found that the apn1 rad1 and apn1 rad10 double mutants have a growth defect and are significantly more sensitive to MMS killing than apn1 rad2 and apn1 rad4 double mutants in a gradient plate assay. | Methyl Methanesulfonate | DNA-(apurinic or apyrimidinic site) lyase APN1 | Saccharomyces cerevisiae S288C |
| 3 | It was found that the apn1 rad1 and apn1 rad10 double mutants have a growth defect and are significantly more sensitive to MMS killing than apn1 rad2 and apn1 rad4 double mutants in a gradient plate assay. | Methyl Methanesulfonate | DNA-(apurinic or apyrimidinic site) lyase APN1 | Saccharomyces cerevisiae S288C |
| 4 | It was found that the apn1 rad1 and apn1 rad10 double mutants have a growth defect and are significantly more sensitive to MMS killing than apn1 rad2 and apn1 rad4 double mutants in a gradient plate assay. | Methyl Methanesulfonate | DNA-(apurinic or apyrimidinic site) lyase APN1 | Saccharomyces cerevisiae S288C |
| 5 | It was found that the apn1 rad1 and apn1 rad10 double mutants have a growth defect and are significantly more sensitive to MMS killing than apn1 rad2 and apn1 rad4 double mutants in a gradient plate assay. | Methyl Methanesulfonate | DNA-(apurinic or apyrimidinic site) lyase APN1 | Saccharomyces cerevisiae S288C |
| 6 | Furthermore, the apn1 rad1 double mutant increased both the spontaneous and MMS-induced mutation frequency. | Methyl Methanesulfonate | DNA-(apurinic or apyrimidinic site) lyase APN1 | Saccharomyces cerevisiae S288C |