Title : Expression of cytochrome P450 genes encoding enzymes active in the metabolism of tamoxifen in human uterine endometrium.

Pub. Date : 1998 Feb

PMID : 9498238






2 Functional Relationships(s)
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1 Expression of cytochrome P450 genes encoding enzymes active in the metabolism of tamoxifen in human uterine endometrium. Tamoxifen cytochrome P450 family 4 subfamily F member 3 Homo sapiens
2 These data suggest that the human endometrial epithelium has the potential of producing CYP enzymes known to generate genotoxic intermediates from tamoxifen and metabolites that affect oestrogen receptors. Tamoxifen cytochrome P450 family 4 subfamily F member 3 Homo sapiens