Title : Mechanisms of amphetamine action revealed in mice lacking the dopamine transporter.

Pub. Date : 1998 Mar 15

PMID : 9482784






4 Functional Relationships(s)
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1 Mechanisms of amphetamine action revealed in mice lacking the dopamine transporter. Amphetamine solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 Mus musculus
2 AMPH can act on both vesicular storage of DA and directly on the dopamine transporter (DAT). Amphetamine solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 Mus musculus
3 AMPH can act on both vesicular storage of DA and directly on the dopamine transporter (DAT). Amphetamine solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 Mus musculus
4 Thus, the DAT is required for the releasing action, but not the vesicle-depleting action, of AMPH on DA neurons, and the latter represents the rate-limiting step in the effects of AMPH. Amphetamine solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 Mus musculus