Title : Small GTP-binding protein Rho stimulates the actomyosin system, leading to invasion of tumor cells.

Pub. Date : 1998 Feb 27

PMID : 9478968






3 Functional Relationships(s)
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1 These results suggested that 1) the Rho signaling pathway and actomyosin system were linked in the transmigration of tumor cells, and 2) expressed active RhoA enhanced LPA-induced tumor cell invasion via the activation of endogenous RhoA pathway, indicating a positive feedback mechanism in the activation of RhoA. lysophosphatidic acid ras homolog family member A Homo sapiens
2 These results suggested that 1) the Rho signaling pathway and actomyosin system were linked in the transmigration of tumor cells, and 2) expressed active RhoA enhanced LPA-induced tumor cell invasion via the activation of endogenous RhoA pathway, indicating a positive feedback mechanism in the activation of RhoA. lysophosphatidic acid ras homolog family member A Homo sapiens
3 These results suggested that 1) the Rho signaling pathway and actomyosin system were linked in the transmigration of tumor cells, and 2) expressed active RhoA enhanced LPA-induced tumor cell invasion via the activation of endogenous RhoA pathway, indicating a positive feedback mechanism in the activation of RhoA. lysophosphatidic acid ras homolog family member A Homo sapiens