Title : Human neutrophils employ the myeloperoxidase-hydrogen peroxide-chloride system to oxidize alpha-amino acids to a family of reactive aldehydes. Mechanistic studies identifying labile intermediates along the reaction pathway.

Pub. Date : 1998 Feb 27

PMID : 9478947






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The reaction is mediated by hypochlorous acid (HOCl), the major oxidant generated by the myeloperoxidase-H2O2-Cl- system of phagocytes. Hypochlorous Acid myeloperoxidase Homo sapiens
2 The reaction is mediated by hypochlorous acid (HOCl), the major oxidant generated by the myeloperoxidase-H2O2-Cl- system of phagocytes. Hypochlorous Acid myeloperoxidase Homo sapiens
3 Collectively, these results detail the chemical mechanism and reaction intermediates generated during conversion of amino acids into aldehydes by myeloperoxidase-generated HOCl. Hypochlorous Acid myeloperoxidase Homo sapiens