Title : Genetic changes associated with immortalization. A review.

Pub. Date : 1997 Nov

PMID : 9467850






2 Functional Relationships(s)
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1 The first of these TPA states is senescence, and several recent studies have shown that abrogation of p53 function permits temporary escape from senescence that ends in a poorly characterized form of arrest (referred to as p53-minus TPA) in which the pRB and p16INK4 genes appear to be involved. Tetradecanoylphorbol Acetate tumor protein p53 Homo sapiens
2 The first of these TPA states is senescence, and several recent studies have shown that abrogation of p53 function permits temporary escape from senescence that ends in a poorly characterized form of arrest (referred to as p53-minus TPA) in which the pRB and p16INK4 genes appear to be involved. Tetradecanoylphorbol Acetate tumor protein p53 Homo sapiens