Title : Identification of substrates and regulators of the mitogen-activated protein kinase ERK5 using chimeric protein kinases.

Pub. Date : 1998 Feb 13

PMID : 9461566






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Assaying ERK5 activity in immune complexes with one of these substrates, c-Myc, we determined that the ERK5 catalytic domain is activated by V12 H-Ras and to a lesser extent by phorbol ester but not by constitutively active mutants of Raf-1. Phorbol Esters MYC proto-oncogene, bHLH transcription factor Homo sapiens