Pub. Date : 1997 Dec
PMID : 9457703
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | FK506 is inactive by itself and requires binding to an FK506 binding protein-12 (FKBP-12), or immunophilin, for activation. | Tacrolimus | FKBP prolyl isomerase 1A | Rattus norvegicus |
| 2 | FK506 is inactive by itself and requires binding to an FK506 binding protein-12 (FKBP-12), or immunophilin, for activation. | Tacrolimus | FKBP prolyl isomerase 1A | Rattus norvegicus |
| 3 | The nerve regenerative property of this class of agents is separate from their immunosuppressant action because FK506-related compounds that bind to FKBP-12 but do not inhibit calcineurin are also able to increase nerve regeneration. | Tacrolimus | FKBP prolyl isomerase 1A | Rattus norvegicus |