Title : Dopamine induces apoptosis through an oxidation-involved SAPK/JNK activation pathway.

Pub. Date : 1998 Feb 6

PMID : 9452508






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Anti-oxidants N-acetylcysteine and catalase, which serve as scavengers of reactive oxygen species generated by metabolic DA oxidation, effectively block DA-induced JNK activation and subsequent apoptosis. Reactive Oxygen Species mitogen-activated protein kinase 8 Homo sapiens