Title : Formation of nitric oxide-derived inflammatory oxidants by myeloperoxidase in neutrophils.

Pub. Date : 1998 Jan 22

PMID : 9450756






1 Functional Relationships(s)
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1 We have recently demonstrated that nitrite (NO2-), a major end-product of .NO metabolism, readily promotes tyrosine nitration through formation of nitryl chloride (NO2Cl) and nitrogen dioxide (.NO2) by reaction with the inflammatory mediators hypochlorous acid (HOCl) or myeloperoxidase. Nitrites myeloperoxidase Homo sapiens