Title : Suppression of leukotriene formation in RBL-2H3 cells that overexpressed phospholipid hydroperoxide glutathione peroxidase.

Pub. Date : 1998 Jan 23

PMID : 9442035






2 Functional Relationships(s)
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1 Flow cytometric analysis revealed that the rapid burst of formation of lipid hydroperoxides induced by A23187 was suppressed in PHGPx-overexpressing cells as compared with the control lines of cells. Lipid Peroxides glutathione peroxidase 4 Rattus norvegicus
2 These results indicate that PHGPx might be involved in inactivation of 5-lipoxygenase via reductions in levels of the fatty acid hydroperoxides that are required for the full activation of 5-lipoxygenase. Lipid Peroxides glutathione peroxidase 4 Rattus norvegicus