Title : Overexpression of hepatic lipase in transgenic mice decreases apolipoprotein B-containing and high density lipoproteins. Evidence that hepatic lipase acts as a ligand for lipoprotein uptake.

Pub. Date : 1998 Jan 23

PMID : 9442022






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 In both the huBTg,hHLTg+/0 mice and the apoE-/-,hHLTg+/0 mice, plasma cholesterol decreased by 50%. Cholesterol apolipoprotein E Mus musculus
2 Plasma cholesterol and apoB-containing lipoprotein levels were approximately 60% lower in apoE-/-,HL-CAT+/0 mice than in apoE-/- mice. Cholesterol apolipoprotein E Mus musculus