Title : Molecularly cloned mammalian glucosamine-6-phosphate deaminase localizes to transporting epithelium and lacks oscillin activity.

Pub. Date : 1998 Jan

PMID : 9438414






4 Functional Relationships(s)
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1 Since GNPDA is the sole enzyme linking hexosamine systems with glycolytic pathways, we propose that it provides a source of energy in the form of phosphosugar derived from the catabolism of hexosamines found in glycoproteins, glycolipids, and sialic acid-containing macromolecules. Hexosamines glucosamine-6-phosphate deaminase 1 Homo sapiens
2 Since GNPDA is the sole enzyme linking hexosamine systems with glycolytic pathways, we propose that it provides a source of energy in the form of phosphosugar derived from the catabolism of hexosamines found in glycoproteins, glycolipids, and sialic acid-containing macromolecules. Hexosamines glucosamine-6-phosphate deaminase 1 Homo sapiens
3 Evidence that GNPDA can regulate hexosamine stores comes from our observation that transfection of GNPDA into HEK-293 cells reduces cellular levels of sialic acid. Hexosamines glucosamine-6-phosphate deaminase 1 Homo sapiens
4 Evidence that GNPDA can regulate hexosamine stores comes from our observation that transfection of GNPDA into HEK-293 cells reduces cellular levels of sialic acid. Hexosamines glucosamine-6-phosphate deaminase 1 Homo sapiens