Title : Adhesion molecule expression in vascular endothelial cells incubated with cancer cell line supernatant are inhibited by neutrophil elastase inhibitor (ONO-5046.Na).

Pub. Date : 1997 Oct

PMID : 9434321






1 Functional Relationships(s)
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1 In control study, Northern blot analysis revealed that in vitro ICAM-1 mRNA transcripts in the rat endothelial cell line (WK-5) was increased in the presence of purified NE while a specific neutrophil elastase inhibitor (ONO-5046.Na) inhibited ICAM-1 expression. sivelestat intercellular adhesion molecule 1 Rattus norvegicus