Pub. Date : 1997 Nov 14
PMID : 9428666
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | The role of cysteine residues in S100B dimerization and regulation of target protein activity. | Cysteine | S100 calcium binding protein B | Homo sapiens |
2 | Previous studies have demonstrated that the two cysteine residues in the calcium-binding protein S100B are required for its extracellular functions. | Cysteine | S100 calcium binding protein B | Homo sapiens |
3 | In addition, S100B proteins containing two, one or no cysteine residues behaved as dimers in size exclusion chromatography experiments in the presence or absence of calcium as well as in the presence or absence of reducing agent. | Cysteine | S100 calcium binding protein B | Homo sapiens |
4 | In summary, cysteine residues are not necessary for the noncovalent dimerization of S100B, but are important in certain S100B target protein-interactions. | Cysteine | S100 calcium binding protein B | Homo sapiens |