Title : Suppression of the Saccharomyces cerevisiae hac1/ire15 mutation by yeast genes and human cDNAs.

Pub. Date : 1997 Nov 12

PMID : 9409765






2 Functional Relationships(s)
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1 We previously reported that the Saccharomyces cerevisiae ire15 mutation results in an inositol-auxotrophic phenotype, and that human cDNAs can suppress the ire15 mutation (Nikawa, J., 1994. Inositol transcription factor HAC1 Saccharomyces cerevisiae S288C
2 All human cDNAs and yeast multicopy suppressors, which had been isolated as suppressors for the ire15 mutation, were able to suppress the inositol-auxotrophic phenotype but not the defect in KAR2 induction of the hac1-disrupted strain. Inositol transcription factor HAC1 Saccharomyces cerevisiae S288C