Title : Identification of residues in the drug-binding site of human P-glycoprotein using a thiol-reactive substrate.

Pub. Date : 1997 Dec 19

PMID : 9405384






1 Functional Relationships(s)
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1 The drug substrates verapamil, vinblastine, and colchicine protected these mutants against inhibition by dBBn, suggesting that these residues are important for interaction of substrates with P-glycoprotein. Colchicine ATP binding cassette subfamily B member 1 Homo sapiens