Title : Aggregating human platelets stimulate the expression of thrombin receptors in cultured vascular smooth muscle cells via the release of transforming growth factor-beta1 and platelet-derived growth factorAB.

Pub. Date : 1997 Dec 2

PMID : 9403612






2 Functional Relationships(s)
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1 METHODS AND RESULTS: Thrombin receptor expression was assessed by Northern and Western blot analyses and functionally by measuring the release of 6-keto prostaglandin F1alpha. 6-Ketoprostaglandin F1 alpha coagulation factor II, thrombin Homo sapiens
2 Pretreatment of VSMCs with either acidified PDP, or TGF-beta1 increased the alpha-thrombin-stimulated release of 6-keto prostaglandin F1alpha. 6-Ketoprostaglandin F1 alpha coagulation factor II, thrombin Homo sapiens