Title : Impact of CYP2D6 poor metabolizer phenotype on propranolol pharmacokinetics and response.

Pub. Date : 1997 Nov-Dec

PMID : 9399616






3 Functional Relationships(s)
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1 Impact of CYP2D6 poor metabolizer phenotype on propranolol pharmacokinetics and response. Propranolol cytochrome P450 family 2 subfamily D member 6 Homo sapiens
2 We conducted an open-label study to determine the impact of cytochrome P-4502D6 (CYP2D6) on propranolol pharmacokinetics and response in 12 healthy men with CYP2D6 extensive metabolizer (EM) phenotype and 3 healthy men with CYP2D6 poor metabolizer (PM) phenotype. Propranolol cytochrome P450 family 2 subfamily D member 6 Homo sapiens
3 We conducted an open-label study to determine the impact of cytochrome P-4502D6 (CYP2D6) on propranolol pharmacokinetics and response in 12 healthy men with CYP2D6 extensive metabolizer (EM) phenotype and 3 healthy men with CYP2D6 poor metabolizer (PM) phenotype. Propranolol cytochrome P450 family 2 subfamily D member 6 Homo sapiens