Pub. Date : 1997 Dec
PMID : 9398733
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Dose-dependent effects of recombinant human interleukin-6 on glucose regulation. | Glucose | interleukin 6 | Homo sapiens |
| 2 | To examine the effects of interleukin 6 (IL-6), the main circulating cytokine, on glucose metabolism in man, we performed dose-response studies of recombinant human IL-6 in normal volunteers. | Glucose | interleukin 6 | Homo sapiens |
| 3 | By 60 min after the 3 higher IL-6 doses, however, the decline in fasting blood glucose was arrested, and glucose levels increased in a dose-dependent fashion. | Glucose | interleukin 6 | Homo sapiens |
| 4 | By 60 min after the 3 higher IL-6 doses, however, the decline in fasting blood glucose was arrested, and glucose levels increased in a dose-dependent fashion. | Glucose | interleukin 6 | Homo sapiens |
| 5 | In conclusion, sc IL-6 administration induced dose-dependent increases in fasting blood glucose, probably by stimulating glucagon release and other counteregulatory hormones and/or by inducing peripheral resistance to insulin action. | Glucose | interleukin 6 | Homo sapiens |