Title : Differences in active site gorge dimensions of cholinesterases revealed by binding of inhibitors to human butyrylcholinesterase.

Pub. Date : 1997 Dec 2

PMID : 9398183






1 Functional Relationships(s)
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1 The Y337 (F330) in mammalian acetylcholinesterase, which is replaced by A328 in human butyrylcholinesterase, is implicated in the binding of ligands such as huperzine A, edrophonium, and acridines and one end of bisquaternary compounds such as BW284C51 and decamethonium. Edrophonium acetylcholinesterase (Cartwright blood group) Homo sapiens