Title : Topoisomerase-I inhibitors for human malignant glioma: differential modulation of p53, p21, bax and bcl-2 expression and of CD95-mediated apoptosis by camptothecin and beta-lapachone.

Pub. Date : 1997 Nov 27

PMID : 9398050






1 Functional Relationships(s)
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Protein Name
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1 LN-229 cells which have partial p53-wild-type activity show enhanced expression of p53, p21 and bax protein, whereas bcl-2 levels decrease, after exposure to camptothecin. Camptothecin tumor protein p53 Homo sapiens