Title : Regulation of spermidine/spermine N1-acetyltransferase expression by cytokines and polyamines in human hepatocarcinoma cells (HepG2).

Pub. Date : 1998 Jan

PMID : 9397163






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 alpha-Difluoromethylornithine (DFMO) pretreatment, by lowering putrescine and spermidine in HGF- or IL-1 beta-treated cells, prevented the induction of cSAT. Eflornithine interleukin 1 beta Homo sapiens
2 alpha-Difluoromethylornithine (DFMO) pretreatment, by lowering putrescine and spermidine in HGF- or IL-1 beta-treated cells, prevented the induction of cSAT. Eflornithine interleukin 1 beta Homo sapiens
3 DFMO prevented almost completely the enhancement of c-jun mRNA expression by IL-1 beta, and this effect was reversed by exogenous putrescine or spermidine. Eflornithine interleukin 1 beta Homo sapiens