Title : Activation of PKCalpha downstream from caspases during apoptosis induced by 7-hydroxystaurosporine or the topoisomerase inhibitors, camptothecin and etoposide, in human myeloid leukemia HL60 cells.

Pub. Date : 1997 Dec 12

PMID : 9395460






2 Functional Relationships(s)
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1 We previously demonstrated that the anticancer agent and protein kinase C (PKC) inhibitor 7-hydroxystaurosporine (UCN-01) induces apoptosis independently of p53 and protein synthesis in HL60 cells. 7-hydroxystaurosporine tumor protein p53 Homo sapiens
2 We previously demonstrated that the anticancer agent and protein kinase C (PKC) inhibitor 7-hydroxystaurosporine (UCN-01) induces apoptosis independently of p53 and protein synthesis in HL60 cells. 7-hydroxystaurosporine tumor protein p53 Homo sapiens